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Copyright 1996-2019 Cerner Multum, Inc. Spironolactone acts as an anti-androgen in two ways. First, it slows down the production of androgens in the adrenal glands and ovaries. Second, it blocks the action of androgens in part by preventing dihydrotestosterone DHT from binding to its androgenetic receptor. Cimetidine Tagamet Cimetidine, brand name Tagamet, belongs to a class of histamine blockers used mainly to treat gastrointestinal ulcers.

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